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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Invest Dermatol. 2012 Apr 5;132(8):2005–2009. doi: 10.1038/jid.2012.98

Table 2.

Identified and Confirmed Nonmelanoma Skin Cancer Cases with Sensitivity, Specificity, Negative (NPV) and Positive Predictive Values (PPV) by Algorithm, 2007-2008. HMO-Enrollee Claims Data.

Identification
Algorithm		 True
Positive
Cases		 Identified
Cases by
Algorithm		 Confirmed
True Cases
Identified
by
Algorithm		 Sensitivity
(95% CI)		 Specificity
(95% CI)		 NPV
(95% CI)		 PPV
(95% CI)
ICD-9-CM
code alone		 2506 2209 1639 65.4
(63.5-67.3)		 95.5
(95.2-95.9)		 93.4
(93.0-93.8)		 74.2
(72.4-76.0)
CPT code
alone		 2506 2059 1610 64.2
(62.4-66.1)		 96.5
(96.2-96.8)		 93.2
(92.8-93.7)		 78.2
76.4-80.0)
Both ICD-9-
CM and CPT
codes		 2506 1534 1230 49.1
(47.1-51.0)		 97.6
(97.4-97.9)		 90.7
(90.2-91.2)		 80.2
(78.2-82.2)

HMO, Health Maintenance Organization; PPV, Positive Predictive Value; CI, Confidence Interval; ICD- 9-CM, International Classification of Diseases, 9th Revision, Clinical Modification; CPT, Current Procedural Terminology.

Study Population: large integrated health system, HMO Health Plan Enrollees, southeastern MI USA.

Standard: Co-Path3 electronic histopathology data.

Total Skin Pathology Cases: 15,297