Table 1.
Correlation of MA-CPP with D1 preference and locomotor phenotypes in AIL mice.
| Phenotype | D8 CPP (s) | D8-D1 CPP (s) |
|---|---|---|
| D1 preference (s) | 0.05 | -0.69* |
| D8 CPP (s) | 1 | 1 |
| D8-D1 CPP (s) | -0.69* | 1 |
| D1 ACT (cm) | 0.13 | 0.03 |
| D8 ACT (cm) | 0.07 | 0.05 |
| MA-ACT (cm) | 0.05 | -0.09 |
| SAL-ACT(cm) | 0.03 | 0.03 |
N = 105 (10 dams, 10 sires, 85 offspring). The variables include time spent on thedrug-paired side on D1 (D1 preference) and D8 (D8 CPP), difference in time spent on the drug-paired side (D8’D1 CPP), locomotor activity during preference assessment on D1 and D8 (D1 ACT and D8 ACT), and the average locomotor activity during MA trials (D2, D4; MA-ACT) and SAL training trials (D3, D5; SAL-ACT). *p < 0.05 for Pearson’s correlation coefficient..