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Representative Western blots show TDP-A and TDP-B upregulate cleaved PARP and pH2AX. Western blot analysis of A) cleaved PARP and B) pH2AX after 24 h of treatment with 10 nM FK228, TDP-A and TDP-B in NCI/ADR-RES, OVCAR-8 and SKOV-3 ovarian cancer cells. The loading controls in A) and B) were β-actin and histone H3, respectively.
