Table 3.
Comparison of the performance measures of DR_Bind, BindN+ and NAPS using the same data set of 15 DNA-bound protein structures with no or insufficient close homologsa
Server | DR_Bind | BindN+ | NAPS |
---|---|---|---|
TP | 110 | 230 | 34 |
FP | 122 | 618 | 115 |
TN | 2585 | 2089 | 2592 |
FN | 292 | 172 | 368 |
Precision | 0.47 | 0.27 | 0.23 |
Sensitivity | 0.27 | 0.57 | 0.08 |
Specificity | 0.95 | 0.77 | 0.96 |
Accuracy | 0.87 | 0.75 | 0.84 |
mcc | 0.29 | 0.26 | 0.07 |
aThe PDB entries are listed in Supplementary Table S2; the total number of residues in the data set is 3109, out of which 402 residues are DNA-binding (=TP+FN) and 2707 residues are non DNA-binding (=FP+TN).