Table 2.
Parameters | Control group | Gentamicin group | Ursolic acid 2 mg/kg |
Ursolic acid 5 mg/kg |
Ursolic acid 10 mg/kg |
---|---|---|---|---|---|
Serum urea (mg/dL) | 41.17 ± 0.703 | 162.33 ± 9.922* | 137.83 ± 4.643** | 99 ± 2.646** | 41.33 ± 2.692** |
Serum uric acid (mg/dL) | 1.62 ± 0.305 | 3.13 ± 0.123* | 2.42 ± 0.108** | 1.57 ± 0.128** | 1.32 ± 0.14** |
Serum Creatinine (mg/dL) | 0.58 ± 0.075 | 6.85 ± 0.348* | 5.63 ± 0.390** | 2.42 ± 0.295** | 0.92 ± 0.054** |
Blood urea nitrogen levels (mg/dL) | 19.24 ± 0.329 | 75.86 ± 4.636* | 64.41 ± 2.17** | 46.26 ± 1.236** | 19.31 ± 1.258** |
Values are mean ± SEM.
*P < 0.001 when compared to the normal control.
**P < 0.001 when compared to gentamicin induced nontreated disease control.