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In vivo activity following a single oral dose of 400 mg/kg of selected 3-alkoxy-1,2-dioxolanes against E. caproni in mice
| Group | No. of mice investigated | No. of mice cured | Worms | TWR (%) | P value |
|---|---|---|---|---|---|
| Control | 4 | 0 | 23.0 (0) | − | − |
| 15 | 4 | 0 | 19.0 (7.2) | 17.4 | 0.2 |
| 16 | 4 | 0 | 27.8 (4.5) | 0 | 0.2 |
| 17 | 4 | 0 | 23.0 (7.8) | 0 | 0.5 |
TWR, total worm burden reduction.
