Table 3.
Variable (not adjusted for other factors) | Sample size for each model | Survival Hazard Ratio (95% CI) | p-value |
---|---|---|---|
Performance Status: 1 vs. 0 | 241 | 1.91 (1.47, 2.49) | <0.0001 |
Lung Metastases: Yes vs. No | 241 | 0.76 (0.58, 1.00) | 0.051 |
Male vs. Female | 241 | 0.91 (0.69, 1.20) | 0.49 |
Measurable vs. Evaluable Disease | 241 | 1.12 (0.82, 1.52) | 0.49 |
Alkaline Phosphatase+: | 238 | 1.42 (1.10, 1.85) | 0.008 |
Calcium+: | 65 | 1.18 (0.71, 1.95) | 0.53 |
Hemoglobin+: | 241 | 0.73 (0.56, 0.94) | 0.015 |
TSH+: | 188 | 1.00 (0.75, 1.34) | 0.99 |
Age+: | 241 | 0.92 (0.71, 1.19) | 0.54 |
Weight loss+: # | 198 | 1.26 (0.95, 1.68) | 0.11 |
BUN+: | 231 | 1.01 (0.77, 1.31) | 0.96 |
Creatinine+: | 236 | 0.94 (0.72, 1.22) | 0.64 |
Progression within first 90 days*: Yes vs. No | 194 | 2.04 (1.50, 2.79) | <0.0001 |
Patient must be alive 90 days post-randomization to be included in the analysis
Estimated weight loss in Kg over 6 months
Hazard ratios compare values above vs. below the median