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. 2012 Mar 21;110(2):373–381. doi: 10.1093/aob/mcs049

Fig. 10.

Fig. 10.

Model for the activation of GA reactions. GA signalling is initiated by the interaction between the GA molecule and the GA receptor protein GID1 to form a complex with DELLA proteins, negative regulators of GA reactions. The GA–GID1–DELLA complex is recognized by the SCFGID2/SLY1 complex and DELLA proteins are polyubiquitinated, resulting in the degradation of DELLA proteins by the 26S proteasome machinery. By GA-initiated degradation of DELLA proteins, through the ubiquitin–proteasome system, the GA-related genes are expressed and GA reactions are activated.