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. Author manuscript; available in PMC: 2013 May 21.
Published in final edited form as: Biotechnol Prog. 2012 May 21;28(3):846–855. doi: 10.1002/btpr.1542

Table 4.

Antigen affinities of the mAb 277 Ala and Gly variants determined by BIA analysis

Sample ka (1/Ms) kd (1/s) KD (pM)
277 Ala Std 1.93E+06 1.42E−05 7.35
Ala-138 1.88E+06 1.60E−05 8.49
Gly-26 2.42E+06 1.81E−05 7.47
277 Ala Std 1.85E+06 1.70E−05 9.22