Table 4. Biomarkers for detecting colorectal cancer selected by the multiple logistic regression model.

Biomarkers	Coefficient	Standard error	p value	Lower 95% CI	Upper 95% CI
(Intercept)	−8.32	1.539	<0.0001	−11.71	−5.621
2-hydroxy-butyrate	286.59	71.90	<0.0001	155.0	440.1
Aspartic acid	33.87	14.29	0.0178	7.390	63.85
Kynurenine	1634.96	569.3	0.0041	559.1	2.830E+03
Cystamine	78.78	26.82	0.0033	31.53	137.3

The 4 metabolites selected by multiple logistic regression analysis using the stepwise variable selection method. The results of the analysis are shown in Table 4. The 95% confidence interval (95% CI) for the AUC (0.9097) obtained from ROC analysis ranged from 0.8438 to 0.9495.