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. 2012 Jul 11;7(7):e40606. doi: 10.1371/journal.pone.0040606

Table 2. Associations of rs2230500 with CIMT.

Genetic model	L_CIMT							R_CIMT
	CIMT^*, mm	P ^*	R² ^†	R² ^*	CIMT^‡, mm	P ^‡	R² ^‡	CIMT^*, mm	P ^*	R² ^†	R² ^*	CIMT^‡, mm	P ^‡	R² ^‡
Genotypic model
GG(n = 755)	0.543 (0.055)				0.545 (0.055)			0.533 (0.055)				0.533 (0.055)
AG(n = 386)	0.542 (0.059)	0.792			0.543 (0.059)	0.723		0.530 (0.059)	0.335			0.529 (0.059)	0.388
AA(n = 49)	0.527 (0.063)	0.068	0.007	0.191	0.521 (0.063)	0.015	0.189	0.515 (0.063)	0.046	0.007	0.193	0.508 (0.063)	0.0088	0.181
Global P value		0.188				0.052			0.107				0.028
Dominant model
GG	0.543 (0.055)				0.545 (0.055)			0.533 (0.055)				0.533 (0.055)
AG+AA	0.540 (0.101)	0.452	0.001	0.189	0.541 (0.101)	0.315	0.185	0.528 (0.101)	0.149	0.002	0.191	0.527 (0.101)	0.127	0.177
Recessive model
AG +GG	0.543 (0.042)				0.544 (0.042)			0.532 (0.042)				0.532 (0.042)
AA	0.527 (0.063)	0.071	0.007	0.191	0.521 (0.063)	0.016	0.189	0.515 (0.063)	0.060	0.007	0.192	0.508 (0.063)	0.012	0.180

L_CIMT indicates IMT in far wall of left common carotid arteries; R_CIMT, IMT in far wall of right common carotid arteries.

^*

Adjusted for age, gender, and hypertension diagnosed only on SBP and/or DBP.

^†

The variation explained by rs2230500.

^‡

Adjusted for age, gender, smoking, and hypertension diagnosed only on SBP and/or DBP.

CIMT are expressed as mean (SD).