. 2012 Jul 11;7(7):e40606. doi: 10.1371/journal.pone.0040606

Table 3. Associations of rs2230500 with atherosclerosis diagnosed by CIMT.

Genetic model	Atherosclerosis diagnosed by L_CIMT							Atherosclerosis diagnosed by R_CIMT
	OR (95% CI)^*	P ^*	R² ^†	R² ^*	OR (95% CI)^‡	P ^‡	R² ^‡	OR (95% CI)^*	P ^*	R² ^†	R² ^*	OR (95% CI)^‡	P ^‡	R² ^‡
Genotypic model
GG(n = 755)	1				1			1				1
AG(n = 386)	1.12 (0.82–1.52)	0.479			1.21 (0.88–1.66)	0.243		1.01 (0.73–1.41)	0.941			1.07 (0.76–1.51)	0.709
AA(n = 49)	0.62 (0.27–1.43)	0.257	0.003	0.104	0.47 (0.18–1.23)	0.124	0.099	0.60 (0.24–1.48)	0.267	0.003	0.122	0.44 (0.15–1.27)	0.127	0.112
Dominant model
GG	1				1			1				1
AG+AA	1.05 (0.78–1.42)	0.734	0.0001	0.102	1.11 (0.82–1.51)	0.509	0.093	0.96 (0.70–1.32)	0.805	0.001	0.121	0.99 (0.71–1.38)	0.931	0.107
Recessive model
AG +GG	1				1			1				1
AA	0.59 (0.26–1.37)	0.220	0.003	0.103	0.44 (0.17–1.15)	0.093	0.097	0.60 (0.25–1.46)	0.260	0.002	0.122	0.43 (0.15–1.23)	0.115	0.112

L_CIMT indicates IMT in far wall of left common carotid arteries; R_CIMT, IMT in far wall of right common carotid arteries.

Adjusted for age, gender, and hypertension diagnosed only on SBP and/or DBP.

^†

The variation explained by rs2230500.

^‡

Adjusted for age, gender, smoking, and hypertension diagnosed only on SBP and/or DBP.