Table 4. Association of rs2230500 with complement C3.

Genetic model	n = 1190
	ComplementC3(mg/dL)*	P *	R2 †	R2 *	ComplementC3(mg/dL)‡	P ‡	R2 ‡
Genotypic model
GG(n = 755)	138.6 (35.7)				138.5 (33.0)
AG(n = 386)	133.8 (35.4)	0.028			133.8 (33.4)	0.024
AA(n = 49)	129.4 (34.3)	0.071	0.008	0.026	130.8 (32.9)	0.115	0.086
Global P value		0.029				0.036
Dominant model
GG	138.6 (35.7)				138.5 (33.0)
AG+AA	133.3 (33.4)	0.012	0.007	0.026	133.4 (20.8)	0.012	0.085
Recessive model
AG +GG	136.9 (33.8)				136.9 (33.8)
AA	129.4 (34.3)	0.133	0.003	0.021	130.8 (32.9)	0.207	0.081

^*Adjusted for age and gender.

^†The variation explained by rs2230500.

^‡Adjusted for age, gender, and hs-CRP.

ComplementC3 are expressed as mean (SD).