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. 2012 Jul 11;7(7):e39545. doi: 10.1371/journal.pone.0039545

Figure 5. Pretreatment with D-mannose does not affect accumulation of F50-Liposome-Cy5.5.

Figure 5

(A) Fuc-Liposome- or Liposome-Cy5.5 was administered via the tail vein (50 µl/mouse). The tumor regions of MIA PaCa-2, BxPC-3 and AsPC-1 cells (the back side of a bilateral flank lesion) in the mouse was observed and Cy5.5 accumulation was quantified using the IVIS imaging system at 96 hours after injection. D-mannose (1000-fold of the L-fucose) was injected simultaneously with liposome injection. (B) Total flux of the tumor and liver was calculated by using Living Image software according to the manufacturer’s instructions.