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. 2012 Jul 11;7(7):e39929. doi: 10.1371/journal.pone.0039929

Figure 3. Haplotypes at the LCORL locus on horse chromosome 3 are associated with size.

Figure 3

(A) Haplotypes for five SNPs were inferred with PHASE and (B) have different counts in the set of all little breed horses (American Miniature to Puerto Rican Paso Fino) vs. all big breed horses (Friesian to Shire). (C) For each breed, the count of chromosomes inferred to be carrying each haplotype. (D) Size-associated SNPs on chromosome 3 are adjacent to the LCORL gene. SNP associations from the 16-breed GWA scan are plotted above the genes in this locus. Each gene’s exons (vertical bars), introns (horizontal lines) and direction of transcription (arrow) are indicated. (E) The size of each horse was quantified via a principal components analysis of 33 measurements from the head, neck, trunk and limbs. For each horse, breed membership is plotted vs. PC1-size score.