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. 2012 Jul 11;7(7):e39990. doi: 10.1371/journal.pone.0039990

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This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Time course ventrodorsal radiographs of representative macaques infected with either H2N2 or H2H3. Panels (A), (B), (C) and (D) represent time course radiographs from an individual animal at baseline, 3 dpi, 8 dpi, and 14 dpi infected with human H2N2 influenza virus. Focal interstitial radiographic changes (solid arrows) were noted on 3 dpi and 8 dpi but have resolved by 14 dpi. Panels (E), (F), (G) and (H) represent time course radiographs from an individual animal at baseline, 3 dpi, 8 dpi, and 14 dpi infected with swine H2N3 influenza virus. Focal interstitial changes with consolidation and partial effacement of the cardiac silhouette (open arrow) were noted. Radiographic changes are progressive on 8 dpi and 14 dpi with complete effacement of the cardiac silhouette and consolidation within the entire right hemi-thorax. Radiographic scoring was performed as previously published [21].