Refractory period for the reactivation of ocular dominance plasticity by 10 d of dark exposure. A, Contralateral bias (VEP amplitude C/I) after monocular deprivation as a function of the age at initiation of 10 d of dark exposure (filled circles) compared with age-matched normal reared controls (open circles). VEPs were recorded from the surface of the binocular region of the right visual cortex after 3 d of left eye deprivation; two-way ANOVA, F(4,40) = 25.22, p < 0.0001; *p < 0.05 versus age-matched NR in Tukey's HSD post hoc. B, Normalization of DE VEP amplitudes to age-matched, normal-reared controls. The refractory period is seen in the response of the deprived eye (filled circles) and nondeprived eye (open circles) to monocular deprivation. Two-way ANOVA, F(4,40) = 55.4, p < 0.0001; *p < 0.05 versus age-matched NR in Tukey's HSD post hoc. The gray boxes indicate normal range of VEP C/I.