Table 6.
Results from Univariate (A), and Unweighted and Weighted SCCA (B) Integrative Analyses of Simulated Data
| Analysis approach | Variable/associations | PTTS % (k=0.6) | PTTS % (k=0.3) |
|---|---|---|---|
| (A) Univariate analysis | rs2840075-203302_at | 61 | 25 |
| rs3781281-209155_s_at | 86 | 37 | |
| rs7776847-223298_s_at | 59 | 31 | |
| rs11140525-IC50 | 87 | 58 | |
| rs7776847-IC50 | 66 | 18 | |
| 223298_s_at-IC50 | 100 | 86 | |
| 1554368_at-IC50 | 91 | 79 | |
| (B) Unweighted SCCA | rs11140525 | 61 | 53 |
| rs7776847 | 72 | 41 | |
| 223298_s_at | 66 | 57 | |
| 1554368_at | 33 | 30 | |
| Weighted SCCA | rs11140525 | 63 | 51 |
| rs7776847 | 77 | 40 | |
| 223298_s__at | 86 | 64 | |
| 1554368_at | 77 | 43 |
PTTS, proportion of times the true variables were selected; SCCA, sparse canonical correlation analysis.