Table 1.
|
IC50 (nM) |
|||
---|---|---|---|---|
Groups | HepG2 | HCT-116 | A549 | MCF-7 |
LDM | 0.60 | 0.94 | 0.14 | 0.60 |
hlFVII-LDP | 17.76 | 33.23 | 2.58 | 11.85 |
hlFVII-LDP-AE | 0.50 | 0.43 | 0.15 | 0.64 |
IC, inhibitory concentration; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; LDM, lidamycin; hlFVII, human Factor VII light chain; LDP, the apoprotein of lidamycin; AE, active enediyne.