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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Ther Drug Monit. 2012 Aug;34(4):467–476. doi: 10.1097/FTD.0b013e31825c4ba6

Figure 1.

Figure 1

Standard Pmetrics cycle plot for NPAG to evaluate convergence. By default, the first 20% of the total cycle number are omitted from the plots to magnify the final cycles. All plots should approach a constant slope of 0 as convergence occurs. In this simulated example, there is no additional noise beyond assay noise, so gamma is one in all cycles.