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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Breast Cancer Res Treat. 2012 Apr 4;134(3):1067–1079. doi: 10.1007/s10549-012-2043-3

Fig. 7.

Fig. 7

The effect of stable knockdown of Notch2 protein on BITC-mediated inhibition of cell migration. a Immunoblotting for transmembrane (uncleaved) Notch2 protein using lysate from MDA-MB-231 cells stably transfected with a control shRNA or a Notch2-targeted shRNA. b Representative images depicting migration of MDA-MB-231 cells stably transfected with a control shRNA or a Notch2-targeted shRNA and treated for 24 hours with DMSO (control) or 5 μM BITC (200× magnification). c Quantitation of cell migration in the cells stably transfected with a control shRNA or a Notch2-targeted shRNA and treated for 24 hours with DMSO (control) or 5 μM BITC. Result shown are mean ± SD (n= 3) *Significantly different (P<0.05) between the indicated groups by one-way ANOVA followed by Bonferroni’s multiple comparison test.