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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Neurosci Res. 2012 Apr 14;90(9):1701–1712. doi: 10.1002/jnr.23055

Figure 2. Expression profile of miRNAs in mouse oligodendrocytes.

Figure 2

A. Bar graph showing the expression levels of Dicer1 mRNA after treatment with mock and mouse Dicer1 siRNAs (n=4). **P <0.01 (Student’s t test). B. Shown is the correlation between the miRNA expression fold change in differentiated vs. undifferentiated Oli-neu cells and that in Dicer1 vs. mock siRNA treated Oli-neu cells. r = Pearson’s correlation coefficient (n=145). **p<0.01 (Student’s t test). C. Comparison of relative expression levels of miRNAs in differentiated/undifferentiated and Dicer1/mock siRNA-treated Oli-neu cells. Shown are the bottom 30 miRNAs with a ≥1 fold (in log2) decrease in expression in differentiated vs. undifferentiated (gray bars). Also shown is the fold change in Dicer1 vs. mock siRNA treated Oli-neu cells (black bars). Underlined and enlarged are miRNAs selected for further validation by qRT-PCR. D. Venn diagram showing the overlap of miRNAs expressed in mouse primary oligodendrocyte cells and in Oli-neu cells.