Fig. 4.

Disorder-degree analysis of viral proteins in virus-host interactomes. Mean percentage of residues predicted to be disordered (y axis) within segments of various lengths (x axis) in sequences of viral proteins interacting with cellular proteins. Data from the five virus-host interactomes have been analyzed. Viral ends (black line) are viral proteins having only one human interacting protein. Viral hubs (colored lines) are viral proteins highly connected to human proteins. Various degree thresholds were used to define the set of hubs: at least 15 (violet line), at least 20 (blue line), at least 25 (turquoise line), at least 30 (green line), at least 50 (yellow line), at least 60 (orange line) and at least 100 human interactors (red line).