Table II. Protein overlaps between virus-host interactomes. A. Protein overlaps between full data sets. Overlaps are given as percentages of the number of human proteins targeted by DENV (column 3), EBV (column 4), FLUAV (column 5), HCV (column 6), or VACV (column 7). Stars indicate the level of significance as assessed by random simulation: *: < 5.10−2, **: < 10−3, ***: < 10−4. B. Protein overlaps between full data sets and data sets containing human proteins targeted by at least two proteins of the same virus. Overlaps are given as percentages of the number of human proteins targeted by at least two proteins of DENV (column 3), EBV (column 4), FLUAV (column 5), HCV (column 6), or VACV (column 7). Stars indicate the level of significance as assessed by the hypergeometric distribution: *: < 5.10−2, **: < 10−3, ***: < 10−4.
| A | % | Human proteins targeted by |
||||
|---|---|---|---|---|---|---|
| DENV | EBV | FLUAV | HCV | VACV | ||
| Human proteins targeted by | DENV | 100 | 4.2 (***) | 7.0 (***) | 6.5 (***) | 4.7 (***) |
| EBV | 7.4 (***) | 100 | 13.5 (***) | 14.6 (***) | 7.0 (***) | |
| FLUAV | 5.8 (***) | 6.3 (***) | 100 | 5.5 (***) | 4.7 (***) | |
| HCV | 14.4 (***) | 18.4 (***) | 14.7 (***) | 100 | 11.7 (***) | |
| VACV | 5.3 (***) | 4.5 (***) | 6.4 (***) | 6.0 (***) | 100 | |
| B | % | Human proteins targeted by at least two proteins of |
||||
|---|---|---|---|---|---|---|
| DENV | EBV | FLUAV | HCV | VACV | ||
| Human proteins targeted by | DENV | 100 | 8.5 | 8.8 | 15.8 (*) | 14.3 |
| EBV | 17.6 (*) | 100 | 17.6 | 47.4 (***) | 14.3 | |
| FLUAV | 5.9 | 14.9 (*) | 100 | 7.9 | 21.4 (*) | |
| HCV | 23.5 | 44.7 (***) | 14.7 | 100 | 28.6 | |
| VACV | 11.8 | 2.1 | 5.9 | 7.9 | 100 | |