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. 2012 Jun 19;107(2):382–387. doi: 10.1038/bjc.2012.219

Table 1. Comparison of clinico-pathological characteristics in young vs old women.

Variables ⩽40 years ⩾50 years P -value a
Age (Mean) 34.6 61.8 <0.00
       
Race 162 (%) 100 (%) <0.00
 Caucasian 32 (19.8) 46 (46)  
 African American 54 (33.3) 36 (36)  
 Hispanic 69 (42.6) 16 (16)  
 Other 7 (4.32) 2 (2)  
       
Grade 153 96 <0.00
 1 9 (5.9) 11 (11.4)  
 2 31 (20.2) 47 (49.0)  
 3 113 (73.9) 38 (39.6)  
       
DNA ploidy 150 98 0.11
 Aneuploid 112 (74.7) 64 (65.3)  
 Diploid 38 (25.3) 34 (34.7)  
       
Tumour size (cm) 4.33±3.27 3.30±3.18 0.01
       
Tumour stage 155 97 0.02
 1 37 (23.9) 38 (39.2)  
 2 63 (40.7) 34 (35.0)  
 3 32 (20.6) 19 (19.6)  
 4 23 (14.8) 6 (6.2)  
       
Nodal stage 147 97 0.00
 0 43 (29.2) 48 (49.5)  
 1 77 (52.4) 33 (34.0)  
 2 10 (6.8) 9 (9.3)  
 3 17 (11.6) 7 (7.2)  
       
Clinical stage 161 100 0.00
 I 22 (13) 29 (29)  
 II 61 (38) 40 (40)  
 III 62 (39) 28 (28)  
 IV 16 (10) 3 (3)  
       
Treatment
 Pre-surgical therapy 151 100 0.03
  Yes 56 (37.1) 24 (24)  
  No 95 (62.9) 76 (76)  
  Surgery 141 100 0.00
 Partial mastectomy 53 (37.6) 56 (56)  
 Radical mastectomy 57 (40.4) 19 (19)  
 Total mastectomy 21 (14.9) 24 (24)  
 Bilateral total mastectomy 10 (7.1) 1 (1)  
 Post-surgical therapy 134 71  
  Chemotherapy 36 (26.9) 31 (43.7) 0.00
  Radiation 35 (26.1) 6 (8.4)  
  Chemotherapy and radiation 63 (47.0) 34 (47.9)  
 Hormonal therapy 134 71 0.00
  Yes 70 (52.2) 41 (57.7)  
  No 64 (47.8) 30 (42.3)  
a

P-value <0.05 is significant.