Table 3. Biomarker expression values (%) according to the molecular subtypes and age groups.
|
LUM-A (
n
=38)
|
LUM-B (
n
=75)
|
LUM-HER2 (
n
=29)
|
HER2 (
n
=29)
|
TRIPLE-NEG (
n
=85)
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Mean | P a | Mean | P a | Mean | P a | Mean | P a | Mean | P a |
| Ki67 (%) | ||||||||||
| ⩾50 years | 7.1±3.36 | 0.07 | 33.8±13.9 | 0.00 | 41.7±25.2 | 0.43 | 58.0±26.8 | 0.56 | 67.5±30.2 | 0.05 |
| ⩽40 years | 9.1±3.66 | 48.4±24.2 | 50.8±33.4 | 51.1±29.1 | 62.7±30.3 | |||||
| P53 (%) | ||||||||||
| ⩾50 years | 2.2±3.63 | 0.02 | 6.9±11.6 | 0.03 | 36.3±39.4 | 0.96 | 23.1±42.9 | 0.35 | 31.0±42.5 | 0.22 |
| ⩽40 years | 7.3±16.9 | 18.5±29.8 | 37.0±44.5 | 39.5±41.3 | 43.5±42.0 | |||||
| ER (%) | ||||||||||
| ⩾50 years | 92.5±9.32 | 0.02 | 87.5±17.9 | 0.00 | 83.5±28.1 | 0.97 | NA | NA | ||
| ⩽40 years | 76.6±26.2 | 66.5±35.6 | 83.2±19.3 | NA | NA | |||||
| PR (%) | ||||||||||
| ⩾50 years | 40.4±36.8 | 0.49 | 52.3±40.3 | 0.01 | 25.8±32.7 | 0.38 | NA | NA | ||
| ⩽40 years | 48.9±38.7 | 31.7±32.3 | 37.5±34.6 | NA | NA | |||||
NA=not applicable.
a
P-value of the two-sample t-test.