Table 2. Socio-demographic and clinical characteristics of the two study populations, survivors and controls.
Survivors (
n
=835)
|
Controls (
n
=1670)
|
||||
---|---|---|---|---|---|
n | % | n | % | P -value a | |
Socio-demographic characteristics | |||||
Age (years) | |||||
20–25 | 373 | 44.7 | 746 | 44.7 | n.a.b |
26–30 | 285 | 34.1 | 570 | 34.1 | |
31–35 | 177 | 21.2 | 354 | 21.2 | |
Gender | |||||
Male | 441 | 52.8 | 882 | 52.8 | n.a.b |
Female | 394 | 47.2 | 788 | 47.2 | |
Language | |||||
German | 633 | 75.8 | 1266 | 75.8 | n.a.b |
French/Italian | 202 | 24.2 | 404 | 24.2 | |
Migration backgroundc | |||||
No | 648 | 77.6 | 1296 | 77.6 | nab |
Yes | 187 | 22.4 | 374 | 22.4 | |
Civil status | |||||
Single, divorced or widowed | 732 | 88.5 | 1284 | 76.9 | <0.001 |
Married | 95 | 11.5 | 385 | 23.1 | |
Education | |||||
Compulsory schooling | 70 | 8.0 | 69 | 4.1 | <0.001 |
Vocational training | 379 | 46.0 | 945 | 56.6 | |
Higher secondaryd | 304 | 36.4 | 449 | 26.9 | |
University | 63 | 7.5 | 200 | 12.0 | |
Income | |||||
Unemployed | 110 | 13.2 | 43 | 2.6 | <0.001 |
0–3000 CHF | 239 | 28.6 | 573 | 34.3 | |
3001–6000 CHF | 402 | 48.1 | 819 | 49.0 | |
>6000 CHF | 45 | 5.4 | 235 | 14.1 | |
Number of children | |||||
None | 708 | 84.8 | 1325 | 79.3 | <0.001 |
One | 63 | 7.5 | 169 | 10.1 | |
Two or more | 41 | 4.9 | 176 | 10.5 | |
Body mass index (kg m2) | |||||
<25 | 606 | 72.6 | 1266 | 75.8 | 0.372 |
⩾25 | 203 | 24.3 | 388 | 23.2 | |
Clinical characteristics | |||||
Age at diagnosis (years) | |||||
≤ 4 | 228 | 27.3 | |||
5–8 | 205 | 24.6 | |||
9–12 | 183 | 21.9 | |||
>12 | 219 | 26.2 | |||
Diagnosis | |||||
Leukaemia | 310 | 37.1 | |||
Hodgkin lymphoma | 73 | 8.7 | |||
Non-Hodgkin lymphoma | 83 | 9.9 | |||
CNS tumours | 101 | 12.1 | |||
Embryonal tumourse | 127 | 15.2 | |||
Bone tumours and soft tissue sarcomas | 87 | 10.4 | |||
Otherf | 54 | 6.5 | |||
Therapy | |||||
Surgery only | 81 | 9.7 | |||
Chemotherapy, but no radiotherapy | 394 | 47.2 | |||
Any radiotherapy | 257 | 30.8 | |||
BMT | 95 | 11.4 | |||
Relapse | |||||
No | 710 | 85.0 | |||
Yes | 125 | 15.0 |
Abbreviations: CHF=Swiss Francs; CNS=central nervous system; n.a.=not applicable; BMT=bone marrow transplantation.
Numbers do not always sum up to the total because of missing values.
χ2-test.
Population matched for gender, age, language, region and migration background.
Does not have a Swiss passport or has received the Swiss passport after date of birth or parents originate from another country.
Higher secondary education includes high school, teachers training colleges, technical colleges and higher vocational education.
Includes neuroblastoma, retinoblastoma, Wilms tumour, liver tumour and germ cell tumour.
Includes epithelial neoplasms, malignant melanomas, unspecified malignant tumours and Langerhans cell histiocytosis.