FIGURE 2.
Relationship between MRCs and other stromal cell subsets in SLOs. (A) Pattern of marker expression in stromal cell subsets. Expression levels of MAdCAM-1, CXCL13, and podoplanin/gp38 in FDCs are often weak or undetectable by immunohistochemistry (†). (B) Schematic of a generalized model of SLO development with the locations of stromal cell subsets (left) and a putative genealogy of stromal cell subsets (right). Numbers indicating cell elements in the left drawing represent stromal cell subsets shown in the right scheme. BM, basement membrane; End./Epi., endothelial or epithelial layer.