Table 3.
Variable | Category | Mean FEV1 | 95% CI | P Value |
---|---|---|---|---|
Gender | Male | 2.76 | 2.58, 2.94 | < 0.0001 |
Female | 2.19 | 2.03, 2.35 | ||
Age at Enrollment | 40 | 2.31 | 2.16, 2.47 | 0.01 |
50 | 2.44 | 2.32, 2.57 | ||
60 | 2.56 | 2.42, 2.71 | ||
AUC GranzymeB | 1000 | 2.88 | 2.62, 3.15 | 0.0038 |
2000 | 2.80 | 2.58, 3.02 | ||
3000 | 2.72 | 2.54, 2.90 | ||
4000 | 2.64 | 2.49, 2.78 | ||
5000 | 2.55 | 2.43, 2.68 | ||
6000 | 2.47 | 2.35, 2.59 | ||
7000 | 2.39 | 2.25, 2.53 | ||
8000 | 2.31 | 2.13, 2.48 | ||
9000 | 2.22 | 2.01, 2.44 | ||
10000 | 2.14 | 1.88, 2.40 |
Multivariable analysis of FEV1 (liter/sec) with respect to gender, recipient age and CD8 granzymeBhi frequency assessed by decile