Table 4.
Marsh-Oberhuber classification | |
---|---|
(i) Marsh I: infiltrative lesion, normal villous architecture and mucosa, and IEL increase (>30–40 lymphocytes/enterocytes counted). | |
(ii) Marsh II: hyperplasic lesion; similar to Marsh I with crypt hyperplasia. | |
(iii) Marsh III: destructive lesion, subdivided to the following: | |
(a) partial villous atrophy, | |
(b) subtotal villous atrophy, | |
(c) total villous atrophy. | |
| |
New grading system | |
| |
(i) Grade A (nonatrophic): >25 IELs/100 enterocytes. | |
(ii) Grade B (atrophic): villous-crypt ratio <3 : 1. | |
(iii) Grade B2 (atrophic): no detectable villi. |