Table 2.
The effect of the natural extracts and their combinations on serum lipid levels in Pluronic F-127 induced hyperlipidemia.
| Groups | Serum Lipid Parameters (mg/dL) | ||||
|---|---|---|---|---|---|
| Cholesterol | Triglycerides | HDL | LDL | LDL/HDL | |
| Normal | 75 ± 2 | 64 ± 6 | 39 ± 5 | 65 ± 1 | 1.9 ± 0.2 |
| Control Pl. | 455 ± 30 | 2894 ± 206 | 33 ± 3 | 378 ± 23 | 11.5 ± 0.7 |
| Atorvastatin | 460 ± 14 | 3021 ± 176 | 26 ± 2 | 377 ± 13 | 14.7 ± 1.1 |
| Artichoke | 523 ± 44 | 3504 ± 160 | 41 ± 8 | 415 ± 39 | 11.7 ± 2.3 |
| Turmeric | 487 ± 20 | 3365 ± 153 | 43 ± 2 | 387 ± 18 | 9.1 ± 0.8a |
| PPL | 388 ± 17 | 2888 ± 190 | 50 ± 3 | 308 ± 15a | 6.2 ± 0.5b |
| Garlic | 389 ± 17 | 3020 ± 198 | 25 ± 2 | 313 ± 14a | 12.9 ± 1.4 |
| Comb. 1 | 573 ± 28 | 3723 ± 159 | 57 ± 4 | 472 ± 24 | 8.3 ± 0.4a |
| Comb. 2 | 510 ± 37 | 3253 ± 204 | 54 ± 2 | 413 ± 33 | 7.7 ± 0.7a |
Data presented as means ± SEM with 6 rats in each group. Control Pl.: control group given only Pluronic F-127. PPL: prickly pear leaves. Comb. 1: combination 1 (artichoke, turmeric, and PPL). Comb. 2: combination 2 (artichoke, turmeric, PPL, and garlic). Statistical analysis was done using ANOVA, aP < 0.05, and bP < 0.0001 compared to control Pl.