Table 3.
IV single dose* |
IP single dose* |
IV repeated dose q2dx8* |
IV repeated dose q3dx8* |
|
---|---|---|---|---|
1 | 2 mg/kg | 6.25 mg/kg | 0.6 mg/kgb | 1.5 mg/kg |
9 | 64 mg/kg | 200 mg/kg | 12 mg/kg | 24 mg/kg |
11 | 4 mg/kg | 6.25 mg/kg | ND | ND |
CD-1 mice received intraperitoneal (IP) or intravenous (IV) single injections or repeated injections of the compound every two days (q2dx8) or three days (q3dx8) for 8 days.
Literature data. ND, not determined.