Table 3.
Weighted estimation | Weighted combination | Known phase | ||||||
---|---|---|---|---|---|---|---|---|
Risk model | Haplotype | Hazard ratio | n = 200 | n = 1000 | n = 200 | n = 1000 | n = 200 | n = 1000 |
Moderate effets | A | 1/2.0 | 91 | 94 | 94 | 95 | 94 | 95 |
B | 1/1.75 | 93 | 93 | 94 | 96 | 95 | 95 | |
C | 1.25 | 81 | 76 | 94 | 95 | 94 | 94 | |
D | 1.5 | 94 | 94 | 95 | 95 | 94 | 95 | |
E | 1/1.25 | 92 | 93 | 95 | 95 | 94 | 95 | |
G | 1/1.5 | 92 | 82 | 95 | 96 | 95 | 96 | |
H | 1.75 | 87 | 84 | 93 | 94 | 94 | 95 | |
I | 2.0 | 94 | 91 | 94 | 95 | 94 | 96 | |
Strong SNP effects | A | 1.0 | 90 | 95 | 92 | 95 | 92 | 95 |
B | 1.0 | 94 | 95 | 94 | 96 | 96 | 95 | |
C | 1.0 | 92 | 94 | 95 | 95 | 94 | 95 | |
D | 4.0 | 93 | 96 | 94 | 96 | 94 | 96 | |
E | 4.0 | 90 | 92 | 94 | 94 | 94 | 94 | |
G | 4.0 | 92 | 94 | 94 | 95 | 95 | 96 | |
H | 1.0 | 92 | 95 | 95 | 94 | 94 | 95 | |
I | 4.0 | 92 | 94 | 95 | 95 | 94 | 94 | |
Strong non-SNP effects | A | 1.0 | 94 | 90 | 96 | 94 | 95 | 95 |
B | 1.0 | 93 | 87 | 93 | 92 | 94 | 94 | |
C | 4.0 | 2 | 0 | 96 | 95 | 94 | 95 | |
D | 1.0 | 92 | 94 | 94 | 96 | 93 | 95 | |
E | 4.0 | 84 | 39 | 96 | 95 | 94 | 95 | |
G | 4.0 | 19 | 0 | 95 | 86 | 94 | 94 | |
H | 4.0 | 18 | 0 | 93 | 82 | 94 | 94 | |
I | 1.0 | 86 | 69 | 91 | 88 | 95 | 94 |