Table 5.

Greatest individual decreases in oxygen saturation and FEV₁

Parameter	Disease stratum  Treatment group	Decrease	Baseline measurement	Lowest post-baseline measurement	Assessment at which lowest measurement recorded
Oxygen saturation, greatest % decrease	Asthma stratum
	Placebo	15.2%	98.7%	83.5%	Minute 5
	Regadenoson	12.4%	97.9%	85.5%	Minute 30
	COPD stratum
	Placebo	14.4%	95.2%	80.8%	Hours 3–7
	Regadenoson	12.7%	98.2%	85.5%	Minute 30
FEV1, greatest % decrease	Asthma stratum
	Placebo	0.74 L (32.9%)	2.25 L	1.51 L	Hour 2
	Regadenoson	0.64 L (34.4%)	1.86 L	1.22 L	Minute 15
	COPD stratum
	Placebo	0.50 L (29.9%)	1.67 L	1.17 L	Hour 2
	Regadenoson	0.78 L (44.6%)	1.75 L	0.97 L	Minute 5
FEV1, greatest absolute decrease	Asthma stratum
	Placebo	1.06 L (32.3%)	3.28 L	2.22 L	Minute 15
	Regadenoson	1.11 L (33.1%)	3.35 L	2.24 L	Minute 15
	COPD stratum
	Placebo	0.55 L (28.8%)	1.91 L	1.36 L	Minute 5
	Regadenoson	0.79 L (30.7%)	2.57 L	1.78 L	Minute 15

COPD, Chronic obstructive pulmonary disease; FEV ₁, forced expiratory volume in 1 second.