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. Author manuscript; available in PMC: 2012 Jul 12.
Published in final edited form as: J Immunol. 2009 Apr 1;182(7):4226–4236. doi: 10.4049/jimmunol.0800771

TABLE I. Somatic hypermutation of H-chains from ectopic lymphoid tissue.

Number of mutations
Treatment # of
sequences		 # of
mice		 # of
lipogranulomas		 FR R FR S CDR R CDR S R/S FR R/S
CDR
TMPD 20 2 4 66 39 72 10 1.7 7.2
Mineral oil 20 2 4 23 11 16 2 2 8

FR, sequences from Framework 2 and 3

CDR, sequences from CDR 1 and 2

HHS Vulnerability Disclosure