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| Mouse strain | Immunodeficiency |
|---|---|
| BALB/c | WT |
| C57BL/6 | WT |
| IFN-γ−/− (on BALB/c or C57BL/6 backgound) | Do not produce IFN-γ |
| IRF-1−/− (C57BL/6 backgound) | Defects in CD8+, NK, and γδ T cell development, Th1 cell response |
| IL-1R−/− (C57BL/6 backgound) | Lack IL-1R |
