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Effects of protease inhibitors on cytokine production and calcium response to Alternaria extract. Alternaria extracts were pretreated with pepstatin A agarose (PepA) or control agarose (CA). Alternatively, they were pretreated with protease inhibitors including APMSF and ATBI. Treated extracts were added to the monolayer of BEAS-2B cells and cytokine production and [Ca2+]i response were examined. M ± SE, n = 5. * p < 0.05, 1-way ANOVA with Tukey's test. † p < 0.05, Student's t test.
