Table 2.
Main statistical results of all studies: Boldface indicates a significant difference (P < .05).
| STUDY | LESIONS |
SENSITIVITY, %
|
SPECIFICITY, %
|
POSITIVE PREDICTIVE VALUE, %
|
NEGATIVE PREDICTIVE VALUE, %
|
||||
|---|---|---|---|---|---|---|---|---|---|
| NAKED EYE | DERMOSCOPY | NAKED EYE | DERMOSCOPY | NAKED EYE | DERMOSCOPY | NAKED EYE | DERMOSCOPY | ||
| Argenziano et al22 | All malignant | 54.1 | 79.2 | 71.3 | 71.8 | 11.3 | 16.1 | 95.8 | 98.1 |
| Westerhoff et al23 | Melanoma only | 54.6 | 75.9 | NA | NA | NA | NA | NA | NA |
| Menzies et al24 | All malignant | 40.0 | 55.0 | 84.6 | 89.0 | 25.8 | 40.0 | 91.3 | 93.7 |
| Melanoma only | 37.5 | 53.1 | 84.6 | 89.0 | 20.7 | 34.0 | 92.7 | 94.7 | |
| Dolianitis et al25 | Melanoma only | ||||||||
| • Menzies method | 60.9 | 84.6 | 85.4 | 77.7 | NA | NA | NA | NA | |
| • 7-point checklist | 60.9 | 81.4 | 85.4 | 73.0 | NA | NA | NA | NA | |
| • ABCD rule | 60.9 | 77.5 | 85.4 | 80.4 | NA | NA | NA | NA | |
| • Pattern analysis | 60.9 | 68.4 | 85.4 | 85.3 | NA | NA | NA | NA | |
NA—not applicable.