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The design of the DCCT-EDIC study and the development of late complications (From Nat Rev Endocrinol 2010; 6:665–675, with permission of the publisher [Nature Publishing Group]). RET: retinopathy, ALB: albuminuria, NEU: neuropathy, mALB: microalbuminuria, HYP: hypertension, CVD: cardiovascular diseases.
