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. 2012 Jul 12;7(7):e38980. doi: 10.1371/journal.pone.0038980

Table 1. Patient demographics, clinical parameters and study participation of subjects completing neurocognitive testing (NCT) procedures.

StudyParticipation Clinical parameter Acute HCV/HIV(aHCV) HIV monoinfection(HIVmono) Difference betweengroups, p-value*
Overall Number, n 24 57
Age (years), median [IQR] 41 [36], [44] 47 [39, 56] 0.003
Male gender, n (%) 24 (100) 50 (89) 0.10
Time-elapsed since HIV diagnosis (years), median [IQR] 6 [3], [12] 11 [5], [16] 0.02
Current CD4+(cells/µL), median [IQR] 590 [458, 745] 505 [382, 783] 0.29
Nadir CD4+(cells/µL), median [IQR] 200 [215, 395] 205 [88, 283] 0.01
Receiving antiretroviral therapy, n (%) 17 (71) 54 (95) 0.006
Current plasma HIV viral load below 50 c/mL, n (%) 16 (67) 54 (95) 0.002
HIV viral load of remaining subjects (c/mL), median [IQR] 5797 [1136, 11758] 14182 [1095, 15952] 0.18
Time elapsed since negative HCV RNA test (weeks), median [IQR] 24 [20], [32]
Current ALT (IU), median [IQR] 213 [78, 237]
Peak ALT (IU), median [IQR] 237 [180, 820]
HCV genotype 1, n (%) 21 (88)
Most recent HCV RNA (c/mL), median [IQR] 986855 [56650, 4315528]

Table 1 legend: HCV = hepatitis C virus; RNA: ribonucleic acid; ALT  =  alanine aminotransferase; IU = international units;

1 subject had VL 87 copies/mL at time of assessment, repeat <50 copies/mL, *using Fisher’s exact test or t-test].