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. 2012 Jul 12;7(7):e38980. doi: 10.1371/journal.pone.0038980

Table 3. Results of univariate and multivariate analyses to examine clinical parameters associated with executive function performance, composite speed and basal ganglia mI/Cr ratio.

Cerebral functionassessment result Poorerexecutivefunction Poorerexecutivefunction FasterCompositespeed FasterCompositespeed Higher basalgangliamI/Cr ratio Higher basalgangliamI/Cr ratio
Univariate Multivariate Univariate Multivariate Univariate Multivariate
Clinical parameter p -value [95% CI] p- value [95% CI] p -value [95% CI] p- value [95% CI] p -value [95% CI] p- value [95% CI]
aHCV study group 0.02 [0.09, 1.07] 0.001 [5.8, 20.1] 0.05 [0.99, 0.00] 0.22 [0.3, 0.1] 0.06 [−0.01, 0.32] 0.03 [0.02, 0.35]
Nadir CD4+ count,per 100 cell/uL increase 0.09 [−0.30, 0.02] 0.001 [0.1,0.02] 0.03 [0.33,0.02] 0.10 [0.01, 0.00] 0.09 [−0.10, 0.01] 0.05 [0.11, 0.00]
Current CD4+ count,per 100 cell/uL increase 0.70 [−0.12, 0.08] 0.05 [0.20,0.00] 0.78 [−0.05, 0.03] 0.83 [−0.05, 0.04]
Age, per 10 year increase 0.68 [−0.28, 0.18] 0.59 [−3.9, 2.2] 0.03 [0.02, 0.47] 0.20 [−0.30, 1.30] 0.45 [−0.12, 0.06]
Receiving cART 0.70 [−0.95, 0.65 0.37 [−18.8, 7.1] 0.42 [−0.47, 1.12] 0.79 [−0.34, 0.26] 0.58 [−0.14, 0.24]
Plasma VL,per 1000 c/mL increase 0.37 [−0.38, 0.14] 0.06 [−0.54, 0.01] 0.82 [−0.01, 0.01] 0.59 [−0.01, 0.01] 0.84 [−0.01, 0.01]
Time since HIV diagnosis,per 10 year increase 0.34 [−0.06, 0.02] 0.15 [−0.85, 0.13] 0.57 [−0.03, 0.05] 0.54 [−0.02, 0.01] 0.81 [−1.58, 1.25]