Table 4. Results of univariate and multivariate analyses to examine clinical parameters associated with occipital, parietal and frontal PK11195 Binding Potential (BP).
Cerebral locationof PK11195binding Potential (BP) | Occipital | Occipital | Parietal | Parietal | Frontal | Frontal |
Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |
Clinical parameter | p -value [95% CI] | p- value [95% CI] | p -value [95% CI] | p- value [95% CI] | p -value [95% CI] | p- value [95% CI] |
aHCV study group | 0.10 [−0.15, 0.01] | 0.11 [−0.13, 0.02] | 0.33 [−0.10, 0.03] | − | 0.26 [−0.58, 0.17] | − |
Nadir CD4+ count,per 100 cell/uL increase | 0.65 [−0.02, 0.03] | − | 0.18 [−0.01, 0.03] | − | 0.24 [−0.04, 0.14] | − |
Current CD4+ count,per 100 cell/uL increase | 0.68 [−0.02, 0.03] | − | 0.06 [−0.01, 0.03] | 0.14 [−0.01, 0.02] | 0.13 [−0.02, 0.17] | 0.29 [−0.04, 0.14] |
Age, per 10 year increase | 0.62 [−0.05, 0.03] | − | 0.48 [−0.04, 0.02] | − | 0.35 [−0.87, −0.07] | − |
Receiving cART | 0.06 [−0.19, 0.00] | 0.07 [−0.18, 0.09] | 0.01 [−0.15, −0.02] | 0.03 [−0.14, −0.01] | 0.03 [−0.87, −0.07] | 0.05 [−0.82, 0.02] |