TABLE 1:
Protein complexes related to genes identified in the screening belonging to the group of transcription.
| Category | p value | Number of genes | |||
|---|---|---|---|---|---|
| Input | Total | ||||
| SAGA complex | 1.89E-12 | 7 | 16 | ||
| SWI/SNF transcription activator complex | 1.55E-09 | 5 | 10 | ||
| SAGA-like complex (SLIK) | 2.04E-06 | 3 | 5 | ||
| RNA polymerase II | 2.60E-06 | 4 | 17 | ||
| ADA complex | 4.07E-06 | 3 | 6 | ||
| SBF complex | 3.58E-05 | 2 | 2 | ||
| RNA polymerase I | 7.16E-05 | 3 | 14 | ||
| Kornberg's mediator (SRB) complex | 0.000254 | 3 | 21 | ||
The Munich Information Center for Protein Sequences (Neuherberg, Germany) protein complexes (1142 categories). The analysis was performed using the bioinformatic tool FunSpec. The p values represent the probability that the intersection of a given list with any given functional category occurs by chance. Input, number of genes from the input cluster in a given category. Total, total number of genes included in each category.