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. 2012 Jun 29;4(1):e2012045. doi: 10.4084/MJHID.2012.45

Figure 1.

Figure 1

Malaria Life cycle (partial illustration). Blood stage prophylaxis: Drugs which act on the malaria parasites only within the erythrocytes. (such as: Mefloquine, Chloroquine, Amodiaquine). They have to be continued therefore for 1 month after leaving the malarious area. As can be seen in the figure, late infections will not be prevented. Liver stage prophylaxis: Drugs which act on the malaria parasites within the hepatocytes (such as Primaquine and Malarone). It is sufficient to continue the drug for a few days after leaving the endemic area. However, only primaquine potentially may prevent all types of malaria including the late infection.