Table 1. Numbers of calretinin and calbindin immunoreactive cells within the adult hippocampus and the sexually dimorphic nucleus of the preoptic area following prenatal dexamethasone treatment.
Animals were killed at 60 days old and numbers of immunoreactive cells were counted within an outlined area surrounding the entire CA1 or CA3 subfields of the hippocampus or within a 500 x 500μm square area surrounding surrounding the SDN-POA. Data are expressed as counts per mm².
| Calretinin
|
Calbindin
|
||||
|---|---|---|---|---|---|
| Treatment/Sex | CA1 | CA3 | CA1 | CA3 | SDN-POA |
|
| |||||
| Veh Male | 40.73 ± 3.48 | 30.15 ± 4.87 | 19.88 ± 2.23 | 20.52 ± 2.69 | 145.17 ± 2.89 |
| Dex Male | 50.67 ± 2.24 | 38.14 ± 2.55 | 24.77 ± 2.67 | 27.08 ± 1.43 | 162.33 ± 8.75 |
| Veh Female | 45.24 ± 6.83 | 32.30 ± 4.72 | 22.40 ± 3.52 | 25.51 ± 2.31 | 126.50 ± 8.04* |
| Dex Female | 39.98 ± 8.85 | 30.48 ± 4.15 | 16.58 ± 2.79 | 22.88 ± 2.82 | 122.50 ± 15.31* |
*
indicates a significant main effect of sex (p<.01) by 2-way ANOVA, with females having fewer calbindin-ir cells than males. N=6 per group.