Table 7.
Pharmacokinetic Parameters for 8a and 20q after Oral Administration to Female Mice.
| Compound | Dose (mg/kg) | t1/2 (hr) | Tmax (hr) | Cmax (ng/ml) | AUClast (hr·ng/ml) | AUCinf (hr·ng/ml) |
|---|---|---|---|---|---|---|
| 8a | 100 | 1.5 | 0.08 | 9540 | 6578 | 6937 |
| 20q | 100 | 1.9 | 0.25 | 9767 | 11219 | 11248 |
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