Table 3.
Compounds | EC50 (μM) | CC50 (μM) | SI |
---|---|---|---|
7 | 6.5 | > 500 | > 77 |
1c | 0.3 | 425 | 1417 |
2a | 1.6 | > 500 | > 312 |
2d | 0.3 | 475 | 1583 |
2h | 0.4 | > 500 | > 1250 |
2k | 1.4 | > 500 | > 357 |
2l | 0.5 | > 500 | > 1000 |
3a | 1.7 | > 500 | > 294 |
3b | 0.5 | 450 | 900 |
3c | 0.6 | > 500 | > 833 |
3j | 0.4 | > 500 | > 1250 |
3k | 1.1 | > 500 | > 455 |
3l | 0.4 | > 500 | > 1250 |
3n | 1.7 | > 500 | > 294 |
3p | 0.4 | 400 | 1000 |
3q | 1.3 | 470 | 362 |
3r | 0.6 | > 500 | > 833 |
3s | 0.8 | > 500 | > 625 |
3t | 4.0 | > 500 | > 125 |
3v | 0.4 | > 500 | > 1250 |
4a | 3.2 | > 500 | > 156 |
4b | 0.3 | > 500 | > 1667 |
4c | 0.5 | > 500 | > 1000 |
5c | 8.5 | > 500 | > 59 |
5d | 2.2 | > 500 | > 227 |
5e | 20 | > 500 | > 25 |
EC50: 50% effective concentration, measured by virus yield reduction assay; CC50: 50% cytotoxic concentration, measured by MTT assay; SI: selective index, SI = CC50/EC50.