Table 1.
Antitumor effect of Gl-BSP on Sarcoma 180 in BALB/c mice (n = 10, ).
| Group | Dose (mg kg−1 × days) | Body weight (g) |
Tumor weight (g) | Inhibitory ratio (%) | |
|---|---|---|---|---|---|
| Origin | After | ||||
| Model | – | 20.4 ± 0.5 | 20.4 ± 1.1 | 1.21 ± 0.27 | 0 |
| Gl-BSP | 50 mg kg−1 × 14 | 20.9 ± 0.9 | 20.4 ± 0.9 | 0.84 ± 0.42 | 30.7 |
| 100 mg kg−1 × 14 | 20.5 ± 0.8 | 20.5 ± 1.4 | 0.61 ± 0.47* | 49.1 | |
| 200 mg kg−1 × 14 | 20.9 ± 0.8 | 21.6 ± 0.8** | 0.48 ± 0.39** | 59.9 | |
| CY | 30 mg kg−1 × 7 | 20.4 ± 0.5 | 18.2 ± 1.5 | 0.23 ± 0.11*** | 81.0 |
Mice were implanted with Sarcoma 180 and administrated with Gl-BPS (50, 100, or 200 mg kg−1) or physiological saline intragastrically for 14 days. At the end of experiment, the tumor were removed and weighted. *P < 0.05, **P < 0.01, ***P < 0.001 vs. model group.