Table 3.

Effect of Gl-BSP on spleen lymphocyte proliferation induced by Con A and LPS in S180-bearing mice (n = 5, $\overline{x}\pm \text{s}$).

Group	Dose (mg kg−1 × days)	Proliferation ratio (%)
		Con A (1 mg l−1)	LPS (5 mg l−1)
Normal	–	254.0 ± 8.4	127.0 ± 8.8
Model	–	130.3 ± 8.3###	108.8 ± 7.6##
CY	30 mg kg−1 × 7 (i.p, q.o.d)	105.0 ± 2.1***	71.2 ± 5.7***
Gl-BSP	50 mg kg−1 × 14	184.3 ± 3.4***	115.5 ± 8.9
	100 mg kg−1 × 14	230.5 ± 10.2***	116.8 ± 0.5
	200 mg kg−1 × 14	236.4 ± 6.7***	123.4 ± 5.7*

S180-bearing mice were administrated intragastrically with Gl-BPS (50, 100, or 200 mg kg⁻¹) or physiological saline respectively for 14 days. At the end of experiment, single splenic lymphocytes were adjusted to a concentration of 1 × 10⁶ cells per well in 96-well culture plates with or without ConA 1 mg l⁻¹ or LPS 5 mg l⁻¹, and incubated at 37°C, 5% CO₂ for 72 h. Cell proliferation was estimated based on the method of MTT. ^##P < 0.01, ^###P < 0.001 model group vs. normal group; *P < 0.05, ***P < 0.001 vs. model group.