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. 2012 Jul 13;3:135. doi: 10.3389/fphar.2012.00135

Table 4.

Effect of Gl-BSP on splenic NK cytotoxic activity in S180-bearing mice (n = 5, x¯±s).

Group Dose (mg kg−1 × days) Cytotoxicity (%)
Normal 35.6 ± 2.3
Model 8.3 ± 1.7###
CY 30 mg kg−1 × 7 (i.p, q. o. d) 0.6 ± 0.5***
Gl-BSP 50 mg kg−1 × 14 13.8 ± 1.0**
100 mg kg−1 × 14 21.4 ± 2.9***
200 mg kg−1 × 14 30.3 ± 1.1***

S180-bearing mice were administrated intragastrically with Gl-BPS (50, 100, or 200 mg kg−1) or physiological saline for 14 days, and the splenic NK cytotoxic activity of mice was examined in a 4-h 51Cr assay. Target cell: YAC-1. Effector: target cell = 40:1; ###P < 0.001 model group vs. normal group; **P < 0.01, ***P < 0.001 vs. model group.