Table 4.
Effect of Gl-BSP on splenic NK cytotoxic activity in S180-bearing mice (n = 5, ).
| Group | Dose (mg kg−1 × days) | Cytotoxicity (%) |
|---|---|---|
| Normal | – | 35.6 ± 2.3 |
| Model | – | 8.3 ± 1.7### |
| CY | 30 mg kg−1 × 7 (i.p, q. o. d) | 0.6 ± 0.5*** |
| Gl-BSP | 50 mg kg−1 × 14 | 13.8 ± 1.0** |
| 100 mg kg−1 × 14 | 21.4 ± 2.9*** | |
| 200 mg kg−1 × 14 | 30.3 ± 1.1*** |
S180-bearing mice were administrated intragastrically with Gl-BPS (50, 100, or 200 mg kg−1) or physiological saline for 14 days, and the splenic NK cytotoxic activity of mice was examined in a 4-h 51Cr assay. Target cell: YAC-1. Effector: target cell = 40:1; ###P < 0.001 model group vs. normal group; **P < 0.01, ***P < 0.001 vs. model group.